Prof. Frank Madeo

Professor Frank Madeo

Scientific Advisory Board

One of the most-cited scientists in the field of autophagy, Dr. Frank Madeo discovered the effects of spermidine as an autophagy trigger and age-protective substance. Madeo’s research on longevity-promoting, well​-tolerated compounds spans various model organisms, including humans. His discovery of the role of spermidine in autophagy induction, cell protection and longevity has pioneered a new and fast-growing area of research and product development, including Longevity Labs’ introduction of its spermidineLIFE® dietary supplement.

Dr. Madeo is Director of the Institute for Molecular Biosciences at the Karl-Franzens University in Graz, Austria. Madeo’s research team works to understand mechanisms of aging to develop new treatment approaches for age-related diseases and extend the healthy lifespan. Dr. Madeo also researches cell death models, the role of the mitochondria in the origination of neurodegenerative diseases, plant-based substances for Parkinson’s disease, and beta-amyloid toxicity in models of Alzheimer’s disease.

Dr. Madeo is a member of the American Academy of Microbiology and founder and editor-in-chief of the journal Microbial Cell. He was awarded the Seneca Medal for Aging Research and is a member of the American Academy of Microbiology.